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 Proteomics Seminar Series 2005 - Basel

  Tuesday 15th November 2005

Ausbildungszentrum der UBS
Viaduktstrasse 33
4002 Basel

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Agenda

 9:30  Registration
 9:45

 Welcome and product update
 Winfried Redeker, Spectronex

 10:00

 LTQ OrbitrapTM - A breakthrough in mass spectrometry
 Bernard Delanghe, Thermo Scientific, Bremen

 10:30  Phosphorylation and Methylation of proteins studied by nano-LC LTQ
 Bernd Mueller,Roche, Basel
 11:00  Break
 11:30  Biomarkers of myocardial infarction
 Michaela Scigelova, Thermo Scientific, UK
 12:00  Definitive new approaches for phosphorylation site discovery and analysis
 Ken Miller,Thermo Scientific, CA
 12:30   Buffet Lunch
 13:40  Mass distance fingerprinting of high accuracy LTQ-ICR-FTMS data
 Bertran Gerrits, ETH Zurich 
 14:10  Determination of hetero elements in proteins using high resolution ICP-MS
 Torsten Lindemann, Thermo Scientific, Bremen
 14:30

 Quantitation of serum proteins by 2D-LC
 Günter Böhm - Flux AG, Basel 

 15:00  Close followed by a Cheese & Wine reception

Abstracts

Listed below is a partial list of the presenters for the European Proteomics Seminar Series taking place in Basel; and also, an abstract of the presentations.  Please scroll down the page to view information on presenters and topic abstracts.

(Note: Information for some of the scheduled presenters may not be posted at this time, more updates to follow)


Mass Spectrometric Analysis of Post Translational Modifications ? Insights, Limitations and Challenges

Bernd Müller, F. Hoffmann-La Roche, Basel

Almost 200 natural and artificial posttranslational modifications of proteins and peptides are currently described in the literature. Phosphorylation of proteins is probably the best investigated modification that is involved in several biological events. The analysis of phosphorylation events by mass spectrometry is very challenging due to biological, biochemical and mass spectrometric limitations.


LC-MS and informatics strategies for the biomarker discovery in human plasma

Dr. Michaela Scigelova - Thermo Scientific UK

In this presentation we will discuss the technical aspects (including the experimental design, sample preparation, top-down and bottom-up analysis with LC-MS) and bioinformatics inherent to a differntial investigation of human proteome represented in plasma. The emphasis will be on the proteomics techniques not using isotopically labelled markers, and on the ?high-throughput? processing of the data obtained for a model of a cardiovascular disease.