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Thermo Scientific Pierce offers high purity silylation, alkylation and acylation reagents for use in derivatization for drugs of abuse testing and other GC applications. Silanes are available for deactivating columns or modifying glass surfaces.
For more information or to purchase, please follow the links below.
Acylation Reagents
Acylation is the conversion of compounds that contain active hydrogens (e.g., -OH, -SH and -NH) into esters, thioesters and amides, respectively, through the action of a carboxylic acid or a carboxylic acid derivative.
Alkylation Reagents
Used in derivatization for GC, alkylation represents the replacement of an active hydrogen by an aliphatic or aliphatic-aromatic (e.g., benzyl)group.
Column Conditioners
Columns used for TMS derivatives should be thoroughly conditioned before use.
Monofunctional and Multifunctional Silanes
Make glass and plastic surfaces slippery and inert, or modify them to attach just about anything. Also ideal for deactivating and coating of chromatographic supports.
Silylation Reagents
Silyl derivatives are the most widely used derivatives for GC applications. They are usually formed by the replacement of the active hydrogens from acids, alcohols, thiols amines, amides and enolizable ketones and aldehydes with the trimethylsilyl group.
Solvents
Specially manufactured and packaged to meet the exact needs of siylation and other sensitive derivatization reactions.
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