Label Transfer Reagents

Biotin-labeled or iodinatable heterobifunctional, cleavable crosslinkers that can be used to tag a bait protein and then transfer the tag onto an interacting protein following a binding interaction.

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Sulfo-SBED Biotin Label Transfer Reagent
Sulfo-SBED contains a biotin tag, an amine-reactive NHS ester to label a bait protein, and a photoactivatable aryl azide group to crosslink to interacting (prey) proteins. Cleaving the spacer arm results in transfer of the biotin tag to the prey protein.

Sulfhydryl-based Biotin Label Transfer Reagents
Mts-Atf-Biotin Reagents have methanethiosulfonate and tetrafluorophenyl azide reactive groups and a biotin tag. Reagents allow crosslinking and biotin label transfer between a bait protein's sulhydryl group and interaction sites on an unknown protein.