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 Rigorously tested antibodies for the most precise and accurate detection available.
Our family of validated intracellular antibodies consists of more than 100 antibodies that have been thoroughly tested in siRNA-mediated knockdown experiments to ensure specific Western blot detection of the target proteins. Now you can proceed with confidence knowing that you will detect the correct protein clearly and unambiguously.
Why does siRNA validation matter?
Although it is general assumed that commercially-available primary antibodies detect the specified proteins, many of these have not been adequately validated using appropriate methods. Only gene-specific methods, such as siRNA, are capable of truly validating antibody specificity in whole cell lysates. This is because carefully-planned siRNA experiments involve specific knockdown of protein expression, resulting in the absence or decrease of the specific protein relative to controls.
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