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Cellomics HCS Reagent Kits

Complete, optimized reagent kits for high-content screening (HCS) and analysis (HCA)

Thermo Scientific Cellomics HCS Reagent Kits are powerful tools for cell-based screening and analysis of specific molecular targets and biological parameters. Cellomics HCS Reagent Kits are designed and validated with the Thermo Scientific Cellomics ArrayScan HCS Reader and BioApplication Software, together providing a “Total Solution” for high-content screening. HCS Reagent Kits are also fully compatible with other fluorescence-based HCS platforms and conventional fluorescence microscopy.

View a list of HCS instrumentation compatible with our Cellomics HCS Reagent Kits.

Please choose your product of interest from the list below or search by Therapeutic Area, Cellular Function or Target Class.

CYTOTOXICITY & APOPTOSIS
Apoptosis 1 Multiparameter Autophagy & Proteasome Function: LC3B and Poly-Ubiquitin Detection Caspase 3 Activation Caspase 9 Activation Multiparameter Cell Death Detection BrdU and Ki67 Cell Proliferation Cell Viability Cleaved PARP Detection Cytochrome C Detection	Cytotoxicity 1 (Multiparameter) Cytotoxicity 2 (Multiparameter) Cytotoxicity 3 (Multiparameter) HIF-1 alpha, Phospho-CREB, FOXO3a Neurite Outgrowth Oxidative Stress 1 p53 and p21 Activation Phospho-p53 and p53 Activation

GENOTOXICITY, DNA DAMAGE & REPAIR
BrdU Cell Proliferation Caspase 3 Activation Caspase 9 Activation Ku70/80 Activation MDM2 and p53 Detection Micronucleus Oxidative Stress 1	p53 and p21 Activation Phospho-p53 and p53 Activation Phospho-ATM Activation Phospho-ATM and p53 Activation Phospho-Chk2 Activation Phospho-H2AX Activation MnSOD and Phospho-H2AX Induction

INFLAMMATION & CELL STRESS
BrdU Cell Proliferation Caspase 3 Activation Caspase 9 Activation Cell Motility Cell Spreading CHOP/GADD153 Detection COX-2 Activation Heme Oxygenase 1 Activation Heme Oxygenase 1 and Phospho-p38 Activation Hsp27 and Phospho-Hsp27 Detection Hsp60 and Hsp90-beta Detection Hsp70 and Hsp90-alpha Detection Immunophilin FKBP52 Detection iNOS Activation ERK MAPK Activation Cytoskeletal Rearrangement: F-actin	HIF-1 alpha, Phospho-CREB, FOXO3a MnSOD Induction MnSOD and Phospho-H2AX Induction NFAT Activation NFkB Activation NFkB and c-Jun Activation Oxidative Stress 1 p38 MAPK Activation p53 and p21 Activation Phospho-p53 and p53 Activation Phospho-4E-BP1 Detection Phospho-S6 Detection c-Jun Activation Phospho-JNK Detection STAT1, STAT2 or STAT3 Activation

CELL SIGNALING & TRANSCRIPTION FACTORS
ATF-2 Activation Beta-Catenin Activation COX-2 Activation ERK MAPK Activation FOXO1A Activation FOXO3A, HIF-1a (Transcription Factors) NFAT Activation NFkB Activation NFkB and c-Jun Activation p38 MAPK Activation Oxidative Stress 1 p53 and p21 Activation Phospho-p53 and p53 Activation	Phospho-AKT Activation c-Jun Activation Phospho-c-Jun and Phospho-JNK Detection Phospho-GSK-3 Detection Phospho-CREB Phospho-JNK Detection Phospho-c-Jun and Phospho-JNK Detection PKA Activation PKA and Phospho-CREB Activation PKC-alpha Activation Smad3 and Phospho-CREB STAT1, STAT2 or STAT3 Activation

CELL CYCLE & PROLIFERATION
Cell Cycle I BrdU and Ki67 Cell Proliferation Cyclin B1 Activation Mitotic Index	p53 and p21 Activation Phospho-p53 and p53 Activation Phospho-PLK1 Activation Phospho-Rb Activation

MORPHOLOGY & PHENOTYPIC CHANGES
Cell Motility Cell Spreading	Cytoskeletal Rearrangement: F-actin and Tubulin Neurite Outgrowth

Accessory Reagents
Whole Cell Stain Toolbox Whole Cell Stains (Blue, Green, Orange, Red)	16% Formaldehyde Ampules (w/v), Methanol-free OptiTracker Optical Performance Monitoring