Publications

Peer-reviewed Publications using Dharmacon siRNA Libraries
and Open Biosystems Viral shRNA Libraries

siRNA Libraries

Ohn1, T. et al. (2008) A functional RNAi screen links O-GlcNAc modification of ribosomal proteins to stress granule and processing body assembly. Nature Cell Biology 10(10): 1224-1231. PubMed

Brass, A.L. et al. (2008) Identification of host proteins required for HIV infection through a functional genomic screen. Science 319, 921-926.  PubMed

Krishnan, M.N. et al. (2008) RNA interference screen for human genes associated with West Nile virus infection. Nature. Aug 6. [Epub ahead of print]. PubMed

Tang, W. et al. (2008) A genome-wide RNAi screen for Wnt/β-catenin pathway components identifies unexpected roles for TCF transcription factors in cancer. PNAS 105: 9697-9702. PubMed

Simpson K, et al (2008) Identification of genes that regulate epithelial cell migration using an siRNA screening approach. Nature Cell Biology 10(9): 1027-1038. PubMed

Kolas, N. K. et al. (2007) Orchestration of the DNA-damage response by the RNF8 Ubiquitin Ligase. Science, 318: 1637 - 1640. PubMed

Swanton C, et al. (2007) Regulators of mitotic arrest and ceramide metabolism are determinants of sensitivity to Paclitaxel and other chemotherapeutic drugs. Cancer Cell. 2007 Jun;11(6):498-512. PubMed

Whitehurst AW, et al. (2007) Synthetic lethal screen identification of chemosensitizer loci in cancer cells. Nature. 2007 Apr 12;446(7137):815-9. PubMed

Viral shRNA Libraries

Westbrook T, et al. (2005) A genetic screen for candidate tumor suppressors identifies REST. Cell. Vol. 121: 837–848. PubMed

Gazin C, et al. (2007) An elaborate pathway required for Ras-mediated epigenetic silencing. Nature. Vol. 449: 1073-1077. PubMed

Gobeil S, et al. (2008) A genome-wide shRNA screen identifies GAS1 as a novel melanoma metastasis supressor gene. Genes and Development. 22: 2932-2940. PubMed

Silva JM, et al. (2008) Profiling essential genes in human mammary cells by multiplex RNAi screening. Science. Vol. 319: 617-620. PubMed

Schlabach M, et al. (2008) Cancer proliferation gene discovery through functional genomics. Science. Vol. 319: 620-624. PubMed

Maier B, et al. (2009) A large-scale functional RNAi screen reveals a role for CK2 in the mammalian circadian clock. Genes. Dev. 23: 708-718. PubMed

Draviam VM, et al. (2007) A functional genomic screen identifies a role for TAO1 kinase in spindle-checkpoint signaling. Nature Cell Biology. 9 (5): 556-564. PubMed