Full sequence and PTM characterization of recombinant proteins with analytic LC-Orbitrap MS/MS, software tools and what we still need
Carsten Sonksen1
1Novozyme, Denmark
We are using an analytic LC-Orbitrap system for full sequence characterization of our recombinant proteins, modified proteins and impurities. This task differs in several aspects from the general proteomic attempt of identification or single PTM determination. Different strategies and our data analysis needs are presented.