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Nucleic Acid Synthesis and Labeling
Oligonucleotide Therapeutics
TheraPure® RNA and DNA phosphoramidites meet the purity demanded in oligonucleotide therapeutic manufacturing. Strictly controlled manufacturing processes limit the levels of reactive impurities and reduce the risk of undesirable reactions during synthesis.
Chemical Modifications
Our specialties include:
  • Modifications including O-methyl, TBDMSi, and fluoro
  • Modifications of the 5' position with acid labile, base labile or photolabile groups
  • Base modifications including halogenations and alkylations
Synthesis Supports
We offer several options for solid phase and automated oligonucleotide synthesis
All Biology Needs a Little Chemistry
Thermo Fisher Scientific (Milwaukee) is the global leader in high quality oligonucleotide synthesis and labeling reagents, with expertise in protection chemistries, manufacturing scale up and innovative purification strategies. Our phosphoramidites, labeled amidites and specialized nucleoside compounds are used in many cutting edge nucleic acid diagnostic kits, therapeutics and research products.

E-mail or call 1-877-886-7629 for more information about these products and services.
A New Light on Fluorescent Labels
NuLight® Phosphoramidites and NHS Esters offer high performance choices for fluorescent labeling during and post oligonucleotide synthesis. Labeled oligonucleotides have a wide range of applications in gene research and including microarray experiments and FISH analyses.
Custom Organic Synthesis
Our experience with synthesis and purification from product concept through manufacturing scale up enables us to respond to our customers' demands for new and evolving chemistries.

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