Dialysis is one of the most commonly used techniques to separate sample components based on selective diffusion across a porous membrane. The pore size determines molecular-weight cutoff (MWCO) of the membrane that is characterized by the molecular-weight at which 90% of the solute is retained by the membrane. Thermo Scientific Pierce Slide-A-Lyzer Dialysis Cassettes are a convenient means for dialyzing sample volumes from 100 µl to 30 ml. Low molecular weight contaminant removal, buffer exchange, desalting and concentration can be accomplished with this device. View sample preparation products.