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Silylation Reagents

Reagents for the modification of active hydrogens from acids, alcohols, thiols, amines and other groups with an inert trimethylsilyl (TMS) group. Silylation adds mass and makes compounds more suitable for gas chromatography.



Silylation reagent that reacts quantitatively under relatively mild conditions with a wide variety of compounds to form volatile, stable TMS derivatives.

Powerful trimethylsilyl donor with highly volatile byproducts for excellent GC separations.

TMCS enhances the reactivity of BSTFA for the silylation of difficult to derivatize compounds.

Useful for preparing oximes of steroids and ketoacids prior to silylation.

The most volatile TMS-amide available, forms volatile and thermally stable derivatives for GC/MS applications.

Offers stable TBDMS (tert-butyl-dimethylsilyl) derivatization.

An excellent catalyst for difficult to silylate compounds.

The strongest silylation reagent for hydroxyls?reacts quickly and smoothly with hydroxyl and carboxyl groups.

Tri-Sil BSA is composed of BSA and pyridine making it excellent for unhindered steroids.

HMDS/TMCS (2:1) formulation without solvent.

HMDS/TMCS in pyridine (2:1:10) mixture for one-step derivatization of organic hydroxyl and polyhydroxyl compounds into TMS ethers.

TMSI, BSA, TMCS (3:3:2) catalyzed silylation reagent formulation that converts all classes of hydroxyl groups to TMS ethers.

TMSI in dry pyridine (1.5 mEq/ml) for derivatizing hydroxyl compounds, particularly carbohydrates.