High sensitivity sample analysis in the low nano-mol range
Accurate and reproducible results
Direct injection of international reference materials
Maintenance-free operation
High throughput
Full automation capability
Product Detail
The LC IsoLink is the first high sensitivity interface connecting HPLC with Isotope Ratio MS for the reproducible and accurate on-line determination of 13C/12C isotope ratios. All organic compounds eluting from an HPLC column are analyzed while maintaining the chromatographic resolution. This opens up a whole new world in the application of isotope ratio mass spectrometry.
The LC IsoLink is built to directly address the analysis of polar and thermo-labile compounds. Most of these compounds (such as amino acids, peptides, carbohydrates, nucleotides, alcohols, organic acids, sulfa drugs, and many more) can be chromatographically separated in aqueous phase using inorganic buffers on ion exchange, size exclusion or specific reversed phase HPLC columns. The LC IsoLink enables the on-line high precision determination of the 13C/12C isotope ratio of each separated component.
Metabolism studies
Tracer experiments with amino acids, lipids, carbohydrates
Nucleotide analysis for DNA synthesis rates
Food and food ingredients
Adulteration control of honey and fruit juices
Determination of origin of flavors and nutrients
Analysis of phospholipids, carbohydrates, amino acids and vitamins
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