Designed for medical and pharmaceutical products, the Thermo Scientific Pharma HME co-rotating twin-screw Hot Melt Extruders are built in stainless steel to GMP standard for research, development or small production. A rugged touch screen with microprocessor control enables easy operation and full data acquisition. Easy opening barrels enable complete cleaning.
Benefits:
Reduced clean room area
Consistent, controllable
processing
Suitable for PAT
Reduced product
Changeover time
On-demand production
Minimized scale-up risk
Reliable cleaning
Product Detail
Designed for Pharmaceutical Needs
The horizontally split barrels (up to 40:1 L/D) have a crevice-free, GMP design. Quick release clamps give easy access to screws and process contact surfaces for cleaning or configuration changes. Both barrel liners and the screws themselves can be easily removed for cleaning or product changeover. The barrel is modular, with interchangeable segments for feeding solids and liquids, or for venting. The variable speed AC motors are brushless and therefore low maintenance.
Comprehensive Range of Capabilities
The Thermo Scientific PHARMA HME series is available in 16 mm and 24 mm sizes and complemented by a full range of ancillary equipment for product mixing, and postextrusion processing. Thermo Scientific Pharmaceutical twin-screw Hot Melt Extruder is manufactured with process lengths of 25:1 and 40:1 L/D, for melt compounding pharmaceutical products at rates up to 5 kg/hr.
Features:
Variable speed digital servo drive system 0-500 rpm, 1.25 kW or 0-1000 rpm 2.5 kW andtemperature range up to 300°C.
Horizontally split barrels, in X15TN surgical grade stainless steel, with top half lifting upwards .
A set of shafts fully configured with suitable agitator configuration in X15TN surgical grade stainless steel. Amain feed port, plus additional multi-purpose top feed/vent/injection ports.
Atmospheric vent adaptor and discharge adaptor for strand die or connection to downstream ancillaries.
Pressure measurement system, upstream of extruder discharge (0-100 bar).
Electronic control system, including touch screen control panelwith optional software, the controller can be connected to a separate PC for collection and analysis of data in spreadsheet or graphical format.
Stainless steel stand for extruder, including stainless steel electrical enclosures.
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