siRNA has gained a lot of attention in drug discovery and development due to the ability to selectively silence genes. RNA was long thought to only be DNA's messenger, an intermediary that delivers the genetic code for proteins.
Researchers have now found that double strande RNA can shut down any given gene. Thus siRNA can be used to uncover the function of specific genes, making this technique a valuable tool for validation and functional genomics.
Product Detail
Thermo Scientific custom siRNA
Composed of 18-20 RNA bases with two DNA bases overhang at the 3'-terminus
Available desalted at 15 OD amount or PAGE purified at 4 OD
Custom siRNA - a variety of scales, purification, and modification options are available, including siSTABLE® stability enhanced siRNA, ON-TARGET® siRNA with fewer off-target effects, dyes, alternative bases, linkers, and other modifications to your custom sequence