Custom HeavyPeptides
 
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  Custom HeavyPeptides


Kits for Relative and Absolute Quantitation in Proteomics

HeavyPeptide BASIC and AQUA are the first kits that offer a complete solution for both absolute and relative quantitation of proteins by Mass Spectrometry (MS).™

Protein Quantitation by Mass Spectrometry

One of the key challenges in Proteomics is the quantitation of proteins at very low concentrations in complex protein mixtures. Thermo Fisher Scientific one of the world's leading manufacturers of mass spectrometers has a large base of customers confronted daily with these challenges and was also the first company to install a pilot research center dedicated to Biomarker Discovery (BRIMS2, in Boston, MA)

Carefully listening to these end-users led us to the development of a fast, economical, and easy-to-use solution: Custom HeavyPeptide Basic and AQUA kits.

   Product Detail


HeavyPeptides are isotopically-labelled, non-radioactive custom peptides for Mass Spectrometry (MS) and Nuclear Magnetic Resonance (NMR) Spectroscopy applications. They can be used as sequence-identical internal weight standards for quantitation of proteins and protein mixtures.

Researchers can choose from a variety of custom-made HeavyPeptide kits to preform relative or absolute quantitation, including the AQUA technique, developed by Harvard Medical School. Combined with Thermo Fisher Scientific's high performance range of MS instruments, such as the Finnigan™ LTQ FT™, customers have access to the most powerful tools in Proteomics.

Advantages

  • relative or absolute quantitation
  • higher accuracy, sensitivity and specificity
  • easy to order custom-made HeavyPeptides
  • quantitation of low abundance proteins
  • economically viable for high throughput screening

Applications

  • biomarker discovery and validation
  • pharmacokinetics
  • metabolomics
  • clinical biochemistry (drug and metabolite monitoring)
  • anti-doping testing
  • protein expression rating
  • validation of siRNA experiments
  • cell signaling profiling

 

 
 
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