MicroRNAs (miRNAs) are a growing class of small, noncoding RNAs (17-25nt) that regulate gene expression by targeting mRNAs for translational repression, degradation, or both. To advance research on the function and mechanisms of these molecules, we offer Thermo Scientific Dharmacon miRIDIAN microRNA research products.
Product Detail
Follow the product name links to purchase or get more information.
miRIDIAN microRNA Mimics
• Synthetic miRNA mimics designed to enter miRNA pathway and act as mature miRNA species
• Supplement native miRNA activity to further decrease steady-state protein levels and study gain-of-function effects
miRIDIAN microRNA Inhibitors
• Synthetic miRNA inhibitors designed to specifically target and irreversibly bind endogenous miRNAs
• Suppress native miRNA activity to increase protein levels and study loss-of-function effects
• Novel, proprietary design confers greater potency and longevity of inhibition
miRIDIAN microRNA Mimic and Inhibitor Positive and Negative Controls
• Mimic and Hairpin Inhibitor Positive Controls to evaluate function and determine optimal assay conditions
• Non-targeting Mimic and Hairpin Inhibitor Negative Controls to distinguish between specific and background effects
• Dye-labeled Transfection Controls to optimize delivery conditions for Mimic and Hairpin Inhibitor experiments
miRIDIAN microRNA Mimic and Inhibitor Libraries
• Collections designed for every human, mouse, and rat miRNA in the current Sanger miRBase Registry
• For phenotypic screening and identification of miRNAs within specific cellular pathways or processes
• Now updated to Sanger miRBase Sequence Database version 10.1
0 项目 
