The most frequently used perfluoro acid anhydrides for preparing perfluoroacyl derivatives for GC/MS analysis are Trifluoroacetic Acid Anhydride (TFAA), Pentafluoropropionic Acid Anhydride (PFAA) and Heptafluorobutyric Acid Anhydride (HFAA). These reagents react readily with alcohols, phenols and amines to produce stable, volatile derivatives for TCD, FID and ECD techniques.
Product Detail
Highlights
For preparation of perfluoroacyl derivatives for analysis by GC/MS
React readily with alcohols, phenols and amines, producing stable volatile derivatives for TCD, FID and ECD techniques
Produce corresponding perfluoro acid as a byproduct from the reaction with the active hydrogens from alcohols, phenols, mercaptans and amines
Many compounds can be derivatized directly with anhydride and solvent; however, it is usually recommended that amine bases (such as triethylamine) be used to react with the acidic byproducts and drive the reaction toward completion
Frequently used for drugs-of-abuse confirmation testing by GC/MS; TFAA is used to identify methamphetamine, PFAA is used to identify opiates and benzoylecgonine, and HFAA is used to identify amphetamines and phencyclidine
References TFAA
1.Gilbert, R.B., et al. (1995). A labetalol metabolite with analytical characteristics resembling amphetamines. J. of Analytical Toxicology 19, 84. 2.Verebey, K., et al. (1989). Rapid confirmation of enzyme multiplied immunoassay technique (EMITR) cocaine positive urine samples by capillary gas-liquid chromatography/nitrogen phosphorus detection (GLC/NPD). J. of Forensic Sciences 34, 46. 3.Mule, S., et al. (1988). Confirmation and quantitation of cocaine, benzoylecgonine, ecgonine methyl ester in human urine by GC/MS. J. of Analytical Toxicology 12, 153.
References HFAA
1.Jones, J.B., et al. (1993). A simple wash procedure for improving chromatography of HFAA derivatized amphetamine extracts for GC/MS analysis. J. of Analytical Toxicology 17, 447.
2 Items Total 2,864.00 USD 
