Pentafluoropropanol is commonly used in combination with perfluoro acid anhydrides to make electron capture detection (ECD) derivatives for GC analysis to confirm the presence of drugs of abuse. Pentafluoropropionic acid anhydride (PFAA) is a perfluoro acid anhydride often used to prepare perfluoroacyl derivatives. This reagent reacts readily with alcohols, phenols and amines to produce stable, volatile derivatives for ECD and flame ionization detection (FID). However, adding fluorine atoms, such as Pentafluoropropanol, into compounds to be analyzed greatly enhances detection sensitivity.
Product Detail
Highlights
Purified for GC/MS use
Adding fluorine atoms into compounds to be analyzed greatly enhances the sensitivity of certain detectors for those materials
Used in ECD and GC-MS applications where it is advantageous to introduce fluorine atoms
Carboxylic acids can be derivatized using a two-step reaction involving reaction with an anhydride, followed by a fluorinated alcohol