For alternative selectivity to traditional aromatic phases, we recommend you try the perfluorinated phases of Fluophase columns. The stationary phase of Fluophase PFP contains a perfluorinated phenyl ring, where every hydrogen atom on the phenyl ring is substituted for a fluorine atom. This substitution gives the phase extra interactions with polar samples to extend its selectivity capabilities.
Fluophase PFP is fully endcapped, and is based on a highly base deactivated 100Å pore size silica. The pore size combined with the fluorinated phenyl phase gives the columns moderate hydrophobic retention, and due to the more polar fluorine atoms the columns have a different selectivity to traditional phenyl phases.
The Carbon-Fluorine bond has greater dipole that a Carbon-Hydrogen bond. This dipole character allows the phase to offer greater retention of polar and halogentated compounds, compared to a traditional phase. Fluophase PFP is stable under 100% aqueous conditions, so it is ideal for 0 to 100% organic fast gradients.
Other column dimensions and hardware designs are available. Please contact us for more information if you do not see the exact column that you are interested in.
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