LTQ XL Linear Ion Trap Mass Spectrometer

The LTQ XL™ extends the legendary MSn performance of the LTQ™, incorporating more techniques to generate structural information through Thermo Scientific’s innovations in ion trap technology.  Thermo Scientific's LTQ XL is the only mass spectrometer that offers multiple dissociation techniques, PQD, ETD and CID.  Pulsed Q Collision Induced Dissociation (PQD) is a patented technique that eliminates the low mass cut-off concern inherent with all ion traps.  This results in extensive coverage for predicted and unpredicted metabolites, and the ability to perform peptide quantification using iTRAQ™ labels.

In addition, fast polarity switching for high-sensitivity analysis of unknowns, high resolution isolation (HRI), intelligent Data Dependent™ acquisition, and optional high resolution accurate mass functionality are all tools to help the researcher gain confident structural identification routinely.

LTQ XL – Redefining Performance

• Pulsed Q Dissociation (PQD) for generating more fragments and extending the low mass range
• Electron Transfer Dissociation (ETD) option provides sequence information not available from conventional methods
• High Resolution Isolation (HRI) enables isolation of isobaric mass peaks for cleaner MSⁿ spectra
• Ultra-fast polarity switching for high sensitivty analysis of unknowns
• MS¹⁰
• Unparalleled sensitivity and unmatched MSn spectral quality
• Best coverage for metabolic profiling and proteomics research
• Simultaneous qualitative and quantitative screening
• Automated Data Dependent™ neutral loss for PTM and biotransformation analyses
• Excellent charge state determinations with Ultra ZoomScan^TM
• Platform for LTQ FT Ultra and the LTQ Orbitrap

Applications include:

• Protein identification and quantitative differential expression analysis
• Biomarker studies and PTM identification
• Metabolite identification and quantification
• Drug and forensics screening

• Horserace drug screening
• High-speed LC methods

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