Thermo Scientific TheraPure DNA Phosphoramidites are ideal for the most demanding applications of synthetic DNA oligonucleotides due to controlled levels of critical reactive impurities, controlled water content, and ultra high purity.
Product Detail
TheraPure phosphoramidites are designed for customers that require highly defined impurity profiles and strictly controlled manufacturing processes
Rigorously controlled manufacturing processes minimize levels of reactive P(III) impurities which could be incorporated into the oligonucleotide product and/or result in the accumulation of by-products which can be difficult to remove during purification
Limited residual water improves amidite stability, eliminating the interference with oligonucleotides synthesis that can be caused by excessive water
Process and Supply Chain Control:
A controlled raw material supply chain and established vendor partnerships ensure consistency and security of supply
All TheraPure products use synthetic nucleoside sources from materials of no known animal origin
Processes are strictly controlled and monitored from material procurement through final QC and product release under ISO9001 standards, providing batch-to-batch reproducibility
All TheraPure RNA phosphoramidites are supplied with lot-specific quality control data including HPLC and phosphorous NMR analyses
Flexible Packaging:
Common pack sizes fit most commercially available synthesizers and are in stock for immediate delivery
Custom and bulk packaging, including??multikilogram lots, are available