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APCI/APPI Combination Ion Source

  APCI/APPI Combination Ion Source



The combination APCI/APPI ion source allows for effective ionization of non-polar compounds. This unique ion source provides greater flexibility and the capability to analyze a larger range of compounds without changing hardware.

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The combination APCI/APPI ion source is the result of a collaboration between Thermo and Syagen Technology.  Building on Thermo's proven orthogonal APCI probe, the addition of the Syagen PhotoMateTM light source enables analysis of a wider range of compounds.

The PhotoMate ion source uses a Krypton lamp which emits photons at 10.0 and 10.6 eV. Krypton was carefully selected because these photon energies, while being sufficient to ionize most analytes, are lower in energy than the ionization potentials of common reverse phase LC-MS solvents such as water, methanol and acetonitrile.  The low energy photons result in spectra with virtually no chemical noise and also ensures minimal fragmentation of the analyte allowing the protonated species of the radical cation to be identified.

 
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  • APCI/APPI Combination Ion Source Data Sheet (PDF)