Base protecting groups are easily removed under mild cleavage and
deprotection conditions.
Mild deprotection conditions reduce degradation during final deprotection. They allow for incorporation of dyes and other chemical modifications which may be labile under harsh deprotection conditions.
Product Detail
Thermo Scientific Controlled Pore Glass (CPG) Synthesis supports are offered with 500Å pore size and 40±5µmol/gram loading and recommended for synthesis of RNA oligonucleotides up to 50mers. RNA CPG is provided with 5'DMT and 2'TBDMS protection.
Quality Control
Our controlled raw material supply chain and established vendor partnerships ensure consistency and security of supply. Processes are strictly controlled and monitored from material procurement through final QC and product release under ISO9001 regulations. These validated processes provide batch to batch reproducibility creating consistent performance in oligonucleotide synthesis.
Thermo Fisher Scientific (Milwaukee) is a licensed supplier of PAC protected nucleoside products.
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