For alternative selectivity to traditional alkyl phases, we recommend you try the perfluorinated phases of Fluophase columns. The stationary phase of Fluophase RP contains a perfluorinated C6 chain, where every hydrogen atom on an unsaturated C6 ligand is substituted for a fluorine atom. This substitution gives the phase extra interactions with polar samples to extend its selectivity capabilities.
Fluophase RP is fully endcapped, and is based on a highly base deactivated 100Å pore size silica. The pore size combined with the Fluorinated C6 phase gives the columns moderate hydrophobic retention for neutral samples, but compared to the conventional phases (C18 or C8) it offers a completely new selectivity.
The Carbon-Fluorine bond has a greaterdipole that a Carbon-Hydrogen bond. This dipole character allows the phase to offer greater retention of polar and halogentated compounds, compared to a traditional phase. Fluophase RP is stable under 100% aqueous conditions, so it is ideal for 0 to 100% organic fast gradients.
Other column dimensions and hardware designs are available. Please contact us for more information if you do not see the exact column that you are interested in.
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