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  Rapid In-Process Moisture Determination on a Fluid Bed Dryer
 This study demonstrates that moisture can be accurately measured in-line using the Thermo Scientific Antaris? MX FT-NIR process analyzer equipped with a fiber optic purge probe inserted into a fluid bed dryer.
 The ability to quantify moisture in real-time is critical for optimizing the operation of production dryers. This is especially true for fluid bed dryers in the pharmaceutical industry since ruining one batch of product can be very costly. The goal in any drying process is to reach optimum product moisture using the least amount of energy in the quickest amount of time without sacrificing product quality. If product is over-dried it might not be suitable for sale, energy would have been wasted in the drying process, and the throughput of the dryer would not have been optimized. If product is under-dried it creates operational inefficiency since the dryer will need to be stopped and restarted several times in order to sample for moisture verification. Also, high-moisture product could cause product stability issues during storage and could stick to the faces of tablet presses.

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  Fourier Transform Near Infrared (FT-NIR)