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| Rapid In-Process Moisture Determination on a Fluid Bed Dryer |
| This study demonstrates that moisture can be accurately measured in-line using the Thermo Scientific Antaris? MX FT-NIR process analyzer equipped with a fiber optic purge probe inserted into a fluid bed dryer. |
| The ability to quantify moisture in real-time is critical for optimizing the
operation of production dryers. This is especially true for fluid bed dryers in
the pharmaceutical industry since ruining one batch of product can be very
costly. The goal in any drying process is to reach optimum product moisture
using the least amount of energy in the quickest amount of time without
sacrificing product quality. If product is over-dried it might not be suitable
for sale, energy would have been wasted in the drying process, and the
throughput of the dryer would not have been optimized. If product is under-dried
it creates operational inefficiency since the dryer will need to be stopped and
restarted several times in order to sample for moisture verification. Also,
high-moisture product could cause product stability issues during storage and
could stick to the faces of tablet presses.
>>Complete list of FT-NIR Applications
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