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Conclusion:
The comprehensive, turn-key toxicology screening methodology described in this application note utilizes an LXQ ion trap, and includes an SPE procedure and LC method that enables the identification of 275 compounds in human urine and human plasma. Accompanying ToxID software performs automatic data analysis and reporting. This eliminates the need for manual data interpretation and increases confidence in compound identification. It is worth noting that when compared to other screening methods, the LC-MS/MS screening methodology identifies more analytes.
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