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  App. Note 323: Simultaneous Detection of 88 Pesticides on the TSQ Quantum Discovery Using a Novel LC/MS/MS Method
 Pesticide residues in food are strictly regulated according to the provisions of US Environmental Protection Agency (EPA) CFR Title 40. Several hundred sections in Part 180 detail the maximum pesticide residue (tolerance) for a wide variety of foods.
 A pesticide’s allowable tolerance (measured in ppm) can span several orders of magnitude, depending upon the food source.  To analyze the large numbers of samples whose pesticide treatment history is usually unknown, the US Food and Drug Administration (FDA) uses analytical methods capable of simultaneously determining a number of pesticide residues.

Due to its specificity in identifying compounds, LC/MS/MS is emerging as the technique of choice for identifying and quantifying pesticides.

The objective of this work was to demonstrate the use of the TSQ Quantum Discovery™ in developing an automated, generic, high-throughput LC/MS/MS screening method to simultaneously detect and quantitate nearly 100 pesticides following minimal separation using an HPLC.

To view the complete application note, please download the PDF file.

   Products used for this Application
  PRODUCT #   Product Name   Image  
 IQLAAEGAAXFAGBMANC  TSQ Series Triple Stage Quadrupole Mass Spectrometers      Seleccionar