| Within the drug discovery environment, high sample throughput that provides comprehensive drug metabolite identification and profiling is highly desirable. The rapid LC-MS/MS method made use of Data-Dependent™ acquisitions to study known metabolites and to uncover unexpected metabolites.
The identification and characterization of glyburide along with 19 metabolites was accomplished in a single LC run of approximately three minutes using the fast cycle time, high sensitivity, and excellent spectral quality of this instrument.
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