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  App. Note 384: Determination of Digoxin in Serum by Liquid Chromatography?Tandem Mass Spectrometry
 The goal of this study was to identify and quantify digoxin in serum. This report demonstrates the use of the TSQ Quantum for this application.
 Digoxin is a cardiac glycoside used in the treatment of various heart failures. Moreover, this compound is used at very low concentration due to their toxicity. Identification and quantitation of such a compound, often performed during a classical forensic expertise or for therapeutic drug monitoring, necessitate a sensitive and specific method.

This study aims to describe a method using liquid chromatography/ tandem mass spectrometry and permitting to quantify digoxin at low concentrations.

To read/download the complete application note, please select the link on the left.

   Products used for this Application
  Product #   Product Name   Image  
 IQLAAEGAAXFAGBMANC  TSQ Series Triple Stage Quadrupole Mass Spectrometers      Select