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  App. note 404: Mapping O-GlcNAc and Phosphorylation Sites in C-MYC and CTD Peptides by Electron Transfer Dissociation Mass Spectrometry
 The goal of this note is to demonstrate the utility of Electron Transfer Dissociation (ETD) for mapping of neighboring phosphorylated and O-glycosylation sites in peptides.
 

Dissociation induced by ETD yields extensive peptide sequence information and in addition preserves labile PTMs. The exact sites of O-linked glycosylation and phosphorylation were unambiguously identified in this work.

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   Products used for this Application
  Product #   Product Name   Image  
 IQLAAEGAAVFACZMAIK  LTQ XL Linear Ion Trap Mass Spectrometer      Select
 IQLAAEGABBFACCMAFJ  ETD Fragmentation, Electron Transfer Dissociation      Select