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  App. note 414: Sample Clean-up Strategies for the LC/MS Analysis of Small Molecules in Serum
 This application note successfully demonstrates the useof on-line SEC for the extraction of analytes from serum.
 
  • On-line SEC analysis provides a suitable alternative to off-line SPE for the clean-up of samples in biological matrices.
  • The methodology is robust and reproducible.
  • Unlike off-line SPE, the process can be automated resulting in increased sample throughput, productivity and saving operator time.

To read/download the complete application note, please use the link on this page.
   Products used for this Application
  Product #   Product Name   Image  
 IQLAAEGAAVFACXMAID  LCQ Deca XP MAX      Select
 -  BioBasic SEC (Size Exclusion) Columns   -   Select
 -  1.9 µm Hypersil GOLD Columns      Select
 IQLAAAGAAOFAFHMALP  Surveyor Plus HPLC System      Select
 -  HyperSep C18 SPE Products   -   Select