Conclusion:
IC-MS/MS is a powerful tool used in the quantitation of haloacetic acid samples. When compared to the conventional EPA methods using GC with electron capture, using IC-MS/MS to analyze for haloacetic acids saves analysts several hours of sample preparation because there is no requirement for sample pretreatment.
The resolution between the matrix peaks and haloacetic acids is excellent, which allows for minimum interference in detection. Excellent recoveries and reproducibility were achieved when samples were spiked into a simulated matrix containing 250 mg/L of each of chloride and sulfate, 150 mg/L bicarbonate, 30 mg/L of nitrate and 100 mg/L ammonium chloride preservative for a total
chloride concentration of 316 mg/L. Results are comparable to those achieved in EPA Method 552.2.

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