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| Investigation of Different Sampling Techniques for the Analysis of Capsule Contents by Fourier Transform Near-Infrared Spectroscopy (ISN:0026) |
| Abstract: FT-NIR spectroscopy was investigated as a means for qualitative and quantitative analysis of conventional hard gelatin capsules. |
| Fourier transform near-infrared (FT-NIR) spectroscopy was investigated as a means for qualitative and quantitative analysis of conventional hard gelatin capsules. Analyses were performed with minimal or no sample preparation. Two sampling techniques were explored: intact whole capsule reflectance and reflectance analysis of the capsule contents removed from the shell. The viability of each sampling option was investigated and the effectiveness of FT-NIR for capsule analysis was assessed.
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