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| X SeriesII ICP-MS: Determination of Selenomethionine in Nutritional Supplements |
| This note presents a procedure for the analysis of Se-containing nutritional supplements and the determination of SeMet therein by HPLC-ICP-MS. |
| Se is a multi-isotopic element, where the major isotope at m/z 80 is interfered by the argon dimer (80Ar2+). This note demonstrates the use of the X SeriesII ICP-MS Collision Cell Technology to remove this interference and permit acquisition of chromatographic data with the most abundant Se isotope. Although a certified reference material (CRM) is not yet commercially available, a selenized yeast material currently undergoing a certification procedure was used for method validation. |
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