| In this application note we report separation of loperamide from matrix interference at atmospheric pressure prior to entrance into the mass spectrometer using FAIMS. FAIMS in combination with the LTQ XL linear ion trap mass spectrometer made possible the detection and identification of the target compound loperamide in the presence of a vast excess of the dosing vehicle PEG 600.
The FAIMS-LTQ XL full scan mass spectrum signal to noise and sensitivity for the target compound was significantly increased.
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