Agenda: To eliminate drugs with unsuitable properties as early as possible in the drug development process, pharmacokinetic (PK) screening is getting more and more attention in early drug discovery. Due to the large number of compounds and samples that have to be analyzed at this stage, it becomes a necessity to automate the optimization of the mass spectrometer and data acquisition for each compound.

QuickQuan software is specially designed for high-throughput discovery quantification. After high throughput tuning it stores the tune data in a central database. After tuning, it creates instrument methods for all the compounds and starts acquiring the sequences supplied by a LIMS system or from those created through the graphical interface. The results can then be reviewed and sent back to the LIMS system.

This Webinar will focus on how we make use of a database to combine the initial user input and the tuning parameters. The tuning parameters are obtained during the compound optimization part of the software. Using this information, QuickQuan creates an instrument method can is then used during data acquisition. The layout of the plates used for data acquisition of the sequences can be setup through a graphical interface or imported through a CSV file. Various reports are then generated in a CSV file format for easy connectivity with the LIMS system.

[View Recording]

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