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LCQ Deca Product Support Bulletins
Below are links to PDF electronic documents for each of the Product Support Bulletins that apply to the LCQ Deca. To load the PDF, select any of the links below. (a free copy of Acrobat Reader can be downloaded from www.adobe.com/reader)
PSB118   PSB118 Data Dependent Constant Neutral Loss Scan Function for Identification of Biotransformations Using Thermo Scientific Ion Trap Mass Spectrometers
 
An application of Data Dependent™ constant neutral loss (DDCNL) scanning to identify in vitro metabolites of glyburide is illustrated
 
 
 
PSB116   PSB116 Analysis of Post-Translation Modifications Using a Data Dependent™ Neutral Loss Scan Function 
 

Post-translational modifications, such as phosphorylation and glycosylation, are associated with regulation, location and function of proteins
 
 
 
PSB114   PSB114 Isotope Pattern Recognition Using Metabolite ID 2.0 Software 
 

To demonstrate the capabilities of isotope pattern searching, in-vitro metabolism of diazepam was studied using LC/MS in conjunction with Metabolite ID 2.0 software
 
 
 
PSB107   PSB107 Peak Parking Using the Thermo Scientific LCQ™ Series
 

The sensitivity and selectivity of electrospray mass spectrometry, combined with the on-line sample concentration and desalting capabilities of reverse-phase HPLC, creates a tandem system of choice for the automated, high-throughput analysis of compounds in a mixture
 
 
 
PSB105   PSB105 Dynamic Exclusion™ Technology 
 

As a peak elutes and its intensity crosses the threshold, the on-board processor in the LCQ™ determines the most intense ion and immediately initiates an MS2 scan. In this way, both MS and MS2 spectra are acquired on each component as it elutes
 
 
 
PSB104   PSB104 Normalized Collision Energy™ Technology 
 

For the first time MSn spectra are now as reproducible as electron impact spectra. The combination of Normalized Collision Energy with WideBand Activation™ means that spectral libraries can be built, searched and exchanged
 
 
 
PSB102   PSB102 WideBand Activation™ Technology
 

The resonance excitation process used for MSn in an ion trap device fragments only the selected ion