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LTQ Orbitrap Product Support Bulletins
Below are links to PDF electronic documents for each of the Product Support Bulletins that apply to the LTQ Orbitrap. To load the PDF, select any of the links below. (a free copy of Acrobat Reader can be downloaded from www.adobe.com/reader)
PSB121   PSB121 Enhanced Fragmentation of Small Molecules in a Thermo Scientific LTQ™ Linear Ion Trap Mass Spectrometer Using Stepped Normalized Collision Energy 
 

The Stepped Normalized Collision Energy (SNCE) process applies several different Normalized Collision Energy “steps” to a sample during ion dissociation.
 
 

PSB120

  

PSB120 Advanced Data Dependent™ Analysis for Ion Trap Mass Spectrometers 
 

Data Dependent acquisition using Ion Trap mass spectrometers allows automated real-time decisions for subsequent MSn analysis.
 
 
PSB119   PSB119 Scan Speed vs Cycle Time on an Ion Trap Mass Spectrometer 
 
 

To achieve maximum benefit in an LC/MSn experiment, the series of events starting from the process of filling the ion trap through detecting the ions must be optimized for a chromatographic timescale
 
 
 

 
PSB118   PSB118 Data Dependent Constant Neutral Loss Scan Function for Identification of Biotransformations Using Thermo Scientific Ion Trap Mass Spectrometers 
 
An application of Data Dependent™ constant neutral loss (DDCNL) scanning to identify in vitro metabolites of glyburide is illustrated.
 
 
 
PSB117   PSB117 Radial Ejection and Dual Detection on the Thermo Scientific LTQ Series Linear Ion Trap Mass Spectrometers 
 
 
The LTQ™ Series two dimensional (2D) linear ion trap mass spectrometers, with their unique features, represents a major leap in ion trap technology from the traditional 3D quadrupole ion traps
 
 
 

 
PSB116   PSB116 Analysis of Post-Translation Modifications Using a Data Dependent™ Neutral Loss Scan Function
 

Post-translational modifications, such as phosphorylation and glycosylation, are associated with regulation, location and function of proteins.
 
 
 
PSB114   PSB114 Isotope Pattern Recognition Using Metabolite ID 2.0 Software
 

To demonstrate the capabilities of isotope pattern searching, in-vitro metabolism of diazepam was studied using LC/MS in conjunction with Metabolite ID 2.0 software
 
 
 
PSB105   PSB105 Dynamic Exclusion™ Technology 
 

As a peak elutes and its intensity crosses the threshold, the on-board processor in the LCQ™ determines the most intense ion and immediately initiates an MS2 scan. In this way, both MS and MS2 spectra are acquired on each component as it elutes
 
 
 
PSB104   PSB104 Normalized Collision Energy™ Technology
 

For the first time MSn spectra are now as reproducible as electron impact spectra. The combination of Normalized Collision Energy with WideBand Activation™ means that spectral libraries can be built, searched and exchanged
 
 
 
PSB102   PSB102 WideBand Activation™ Technology
 

The resonance excitation process used for MSn in an ion trap device fragments only the selected ion