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The Thermo Scientific DSQ™ II, a single stage quadrupole mass spectrometer with a curved prefilter that minimizes background noise derived from excited neutrals, was used for the GC/MS confirmation and quantitation a THC metabolite (THCA) in urine. Thermo Scientific ToxLab™ 2.0 software provided automated sample analysis and quantitation, and the method was fully validated, including assessments of precision, interference, and linearity.
The analysis of THCA on the DSQ II was completed with a THCA retention time of less than two minutes. The method was fully evaluated, in matrix, and included linearity, precision, carryover, and specificity testing. The final results accurately reflect method development and validation as they would be performed within a working laboratory.
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