Auto-Dilution
Because there is considerable variability in nature in the relative amounts of C/N/S and H/O, and because the ionization efficiencies of the analyte species differ significantly, Continuous Flow sample preparation leads to a very dynamic range of signal intensities. The ConFlo IV is designed to handle this large and variable dynamic range of elements and isotopes using patented He-dilution technology*. The dilution happens in the open split, at the very last point before transfer into the ion source, eliminating any possible isotopic effects on the sample gas.
*Patent US167537

Reference Gas Injection
For the purpose of sample-standard referencing in Continuous Flow applications, cylinders of calibrated reference gases can be used for extended periods of time. Reference gases are supplied in μL amounts through inert capillaries into the Reference Gas injection port, creating a rectangular, flat-topped peak of reference gas without changing any pressures or gas flows. The use of reference gases instead of reference bulk material for standardization reduces the operational costs by almost 50 % while increasing the sample throughput by almost 50 %. The reference gas consumption is negligible and thus gases can be kept trickling continuously, ensuring constant conditions in the supply lines and pressure regulators.

Automatic Range Control*
The ConFlo IV provides automated adjustment of the intensities of the reference gas pulses. As a consequence - and for the first time - in Continuous Flow Isotope Ratio MS, the reference gas intensities can be matched to the intensities of sample gas pulses. Hence, the fundamental principle of Isotope Ratio MS, equal conditions for sample and reference gases, can be applied to all Continuous Flow applications.
*(Patent pending)