The new Thermo Scientific ITQ™ Series  of GC-ion trap mass spectrometers features two newly available advanced scan functions designed to improve data quality and system ease of use. ACE (Automated Collision Energy) and PQD (Pulsed Q Dissociation Mode) are coupled to the MSⁿ  feature of the ITQ Series.

MSⁿ (MS/MS, n < 5) is a powerful tool that allows for the detection, identification, and quantitation of compounds that cannot typically be detected by other routine GC/MS techniques. These new scan functions, standard with MSⁿ  on the Thermo Scientific ITQ 1100™ GC/MSⁿ  and as an available option for the Thermo Scientific ITQ 700™ and Thermo Scientific ITQ 900™ GC/MS systems, make MSⁿ accessible for routine applications.

ACE - The Power of MSⁿ Made Easy

New, patent-pending Automated Collision Energy (ACE) sets estimated optimal collision energies based on user-specified precursor ions and damping gas flows. During acquisitions, ACE runs three collision energies in a single scan to ensure optimal fragmentation and product ion production. The optimal collision energy no longer needs to be determined experimentally - ACE covers all of the bases every time you run MSⁿ. Plus, any changes to damping gas flows or precursor ions are automatically adjusted for, allowing easy method refinement without repeated optimization experiments.

• Easily apply the power of MSⁿ for routine use
• Three collision energies in each scan - estimated optimal plus a lower and a higher value
• Provides simplified starting point for manual methods

Advanced Pulsed Q Dissociation Mode - For Enhanced MSⁿ Quality

The power of our patented Pulsed Q Dissociation Mode (PQD), originally developed for Thermo Scientific liquid chromatography-linear ion trap mass spectrometers, is now available standard on the ITQ 1100 GC/MSⁿ system. PQD increases overall quality of product ion  spectra, particularly in low mass range. This allows low m/z fragments thater are usually excluded from standard collision induced dissociation (CID) data to be seen. PQD also allows the user to access higher energy dissociation channels than standard CID offers. PQD is a novel fragmentation mechanism that involves precursor activation at a high q, a time delay to allow the precursor to fragment, then a rapid pulse to a low q where all fragment ions are trapped.

• Eliminates low-mass cutoff
• Generates information-rich mass spectral data, even in the low mass range
• Produces precise, reproducible fragmentation.