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  Raman Spectroscopy



What is Raman Spectroscopy?

Raman spectroscopy utilizes the phenomenon of inelastic light scattering to perform non-destructive chemical analysis at macro- and microscopic levels.

This spectroscopic technique investigates the vibrational transitions of covalent bonds in molecules. Raman spectroscopy is applied to a wide range of samples that includes organic and inorganic materials.

Raman is typically applied to  solids and liquids, but occasionally is a good choice for certain gasses. Raman gives important information about a molecules structure that can be used to supply accurate molecular identification of unknowns, and can be used in quantitative and conformational analysis of your samples.


Raman Autosampling Carousel

As a light scattering technique, all that is required for the collection of a spectrum is to place the sample into the excitation beam and collect the scattered light. There are few concerns with sample thickness (as in transmission analyses) and little contribution from the ambient atmosphere. There is no need for high-vacuum or desiccated sample holders.

Glass, water and plastic packaging each have very weak Raman spectra, making the technique even easier to use. Often, samples can be analyzed directly inside the glass bottle or plastic bag without opening the package and risking contamination. Aqueous samples are readily analyzed without the need to remove water. Since ambient humidity is not a problem, there is no need to purge the instrument.


Raman easily samples through glass & other packaging


Typical Raman Applications:

  • Pharmaceutical polymorph characterization
  • Characterization of precipitates in pharmaceutical injectable ampules
  • Carbon nanotube characterization
  • Identification of particulates as small as 1 micron
  • Characterization of defects in LCD manufacturing
  • Identification of embedded particulates
  • Characterization of inclusions and bubbles in glass
  • Forensic trace analysis
  • Semiconductor stess measurements
  • Semiconductor defect analysis
  • Silicon crystalinity measurements
  • Gemstone verification and characterization
  • WMD screening
  • Characterization of defects and contaminants on paper
  • Characterization of coatings on paper
  • Characterization of ancient artwork and archeological relics


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