Life Sciences Mass Spectrometry eNewsletter
Critical Mass Issue 32
Feb 2007
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 LTQ XL with ETD wins Silver Award at Pittcon 2007  
Available for the first time on a linear ion trap mass spectrometer, ETD provides important new peptide structural information not available from conventional collisionally induced dissociation (CID) methods. ETD is a new fragmentation technique that significantly improves protein characterization, post-translational modification (PTM) analysis and top-down or middle-down sequencing of proteins and peptides. The new Thermo Scientific LTQ XL is the only mass spectrometer that offers multiple dissociation techniques, Pulsed Q Dissociation (PQD), ETD and CID.
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 Tip of the Month: Independent Time-Bound Data Dependent Parent and Reject Mass Windows (INTAMS)  
Using INTAMS has several benefits:
- Parent and reject masses can now be defined independent of method segments.
- Each mass entry has its own start and end time.
- Separate parent and reject mass tables can be defined for positive and negative polarity modes.
- Up to 20,000 masses can be assigned to each parent and reject mass table.
See How 

 Food Safety: Mycotoxins in Cattle Forages and Food Matrices  
Mycotoxins are toxic metabolites produced by certain species of fungi that infect and colonize various agricultural crops in the field and during storage. Environmental factors such as temperature and humidity influence the occurrence of these toxins on grains, nuts and other commodities susceptible to mold infestation. In addition, any crop that is stored for more than a few days is a target for mold growth and mycotoxin formation. Most mycotoxins...
Download Full Article [PDF 563 kB] 

 ABRF 2007 Tampa, Florida March 31 - April 3 2007  
Thermo Scientific will be conducting the following workshop this year during the ABRF meeting:
- Complementary Discovery-Based Proteomic Platforms with Targeted Analysis – Dr. Christine Wu; University of Colorado, School of Medicine, Department of Pharmacology
- Linear Ion Traps and the Future of Proteomics: from Electron Transfer Dissociation to Analysis of Single Nucleotide Polymorphisms – Dr. James L. Stephenson, Jr.; Research Triangle Institute
Be sure to register now and reserve your spot for this workshop.
Register Now 

 SMI: Small Molecule Investigation  
Small Molecule Investigation features the ultimate metabolite identification drama. Metabolite ID puts the team's confidence to test! Will they have the speed, sensitivity, and spectral quality they need?
Watch the Video Now and Find Out 

 Obtaining Meaningful Data from Mass Spectrometry is Critical  
Mass spectrometry is instrumental in simplifying complex protein mixtures by identifying unknown compounds, quantifying known compounds, or providing information on the structure and chemical properties of molecules. Regardless of the method used, significant sample handling and processing is often required to perform the desired analysis and receive meaningful data. This issue of Previews highlights several MS sample prep products, including abundant protein removal kits, protein stains, digestion kits, sample clean-up tools, ion pairing reagents and crosslinking reagents.
Request this special MS-focused issue to achieve better MS results! 

 Transcend™ Systems for Online Sample Preparation and Ultra-Fast Chromatography  
Transcend Systems combine the power of online sample extraction, using our patented TurboFlow® technology, with the speed of ultra-fast chromatography for the fastest and cleanest analysis. The new systems eliminate SPE, LLE, or PPT, minimize ion suppression, offer better resolution, faster analysis, increased sensitivity, and can quadruple the throughput of one mass spectrometer. As a result, it takes chromatography standards to new heights. When configured with the TSQ Quantum, the system delivers fast and efficient quantitative results with the lowest ion suppression and chemical noise, resulting in highly sensitive bioanalytical methods, development of more robust methods, and reduction in analytical failures.
Learn More By Visiting this Application Database 

 Separated By Experience eNewsletter  
Covering LC, LC/MS, GC, GC/MS and SPE applications and methodology, the "Separated by Experience" chromatography e-newsletter provides you the technical tips and information to improve your chromatographic analyses. Each issue of the newsletter will cover scientific articles and posters, detailed applications and tips and information on the latest products and literature. If chromatography is an essential part of your work, you cannot miss this opportunity.
Learn More and Register Now 

 All Molecule World Tour: Feb 2 - May 10 2007  
Register to attend a free seminar on the latest LC/MS methods for:
- protein analysis
- compound identification
- bioanalysis
- environmental
- food safety
The tour features presentations by various industry leaders and application experts.
Learn More and Register Now 

 Software Update  
Here are the software updates for February 2007. Make sure to check the version update for LC Devices. Please contact your local sales representative regarding questions on how to upgrade your software.
Note: This list is subject to change without notice as our software is continuously being updated and improved.
View Updates Now 

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 For Additional Information
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