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| QuickQuan-
High-throughput LC/MS for Discovery Quant. |
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Agenda:
To eliminate drugs with unsuitable properties as early as
possible in the drug development process, pharmacokinetic (PK)
screening is getting more and more attention in early drug
discovery. Due to the large number of compounds and samples
that have to be analyzed at this stage, it becomes a necessity
to automate the optimization of the mass spectrometer and data
acquisition for each compound. This Webinar will focus on how
QuickQuan enables high-throughput discovery
Quant...
Speaker: Louis Maljers, Thermo
Electron Corporation |
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Now |
| Quantum Waves:
Bioanalysis - From Sample to Data |
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Bioanalysis is
essential to generate significant data from living species in
order to assess PK and metabolic profiles of drug candidates.
Bioanalysis is not the...
Author: Dr. Jacques
Girault, Ph.D. Senior Director Scientific Client Relations
PAREXEL Poitiers, France (Reproduced with permission from
Parexel's Clinpharm Net News) |
| Download Full
Article (PDF 1.62MB) |
| Software: Confident
Protein ID Searches with BioWorks™ 3.2 |
|
| SEQUEST®
allows the most sensitive searches of protein and peptide
data, delivering highly confident search results without
missing important proteins. BioWorks has been enhanced by a
probability-based scoring algorithm in addition to the
traditional SEQUEST scores. This rigorous score gives SEQUEST
users more confidence that SEQUEST will not miss any important
proteins and that the probability algorithm will provide an
objective likelihood of a hit. The peptide hits are... |
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| Read Full
Article |
| Proteomics
Application: Top-Down Analysis of Human Plasma
Proteome |
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Characterization
of the plasma proteome is a daunting analytical task due to
the large number of proteins thought to be present and the
extremely large dynamic range of their concentrations.
Historically, several different analytical approaches have
been incorporated to identify proteins belonging to the low
molecular weight (LMW) plasma proteome, including various
enrichment schemes and numerous bottom-up mass spectrometric
analyses. For bottom-up analysis, the protein is digested with
an enzyme to give a mixture of peptides which are identified
from database analysis of their CID fragmentation spectra to
lead to the identity of the source protein. By contrast,
top-down analysis enables... |
| Download Full
Application Note (PDF
658KB) |
|
| ABRF Posters &
Presentations CD |
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This CD is packed with all
of Thermo's Posters and Workshops from ABRF covering several
topics within Proteomics including:
- On-line
identification and characterization of glycopeptides using
hybrid ion trap-Fourier transform mass spectrometry
-
Automatic de novo sequencing using
hybrid ion trap- Fourier transform mass spectrometry and
more... |
| Order your FREE
Copy Now |
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| ABRF Workshops
On-Demand |
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The following is a list of
Thermo's technical workshops recorded at ABRF:
- A
new-label free platform for quantitative proteomics By Leo
Bonilla, Ph.D., Director, BRIMS Center, Thermo Electron
Corporation
- Top-down proteomics - A definitive new
approach to intact protein analysis, Andrew Forbes, Ph.D.,
Center for Top-Down Proteomics, University of Illinois at
Urbana-Champaign |
| View Recordings
Now |
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| Applications in Mass
Spectrometry User Meeting, Benelux |
|
A FREE one-day
seminar will highlight Thermo's most recent and advanced mass
spectrometry workflows and their applications in a variety of
laboratories across Benelux. The series includes both guest
speakers and Thermo's application
specialists.
Topics to be discussed
include:
- LC-ESI MS-MS in Proteomic Analysis By J-P
Noben, Ph.D., Biomedical...
- Using the Finnigan™ TSQ™ Quantum for
quantitative and qualitative metab...
and more... |
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Now |
| Special Ion Trap
Offers |
|
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Choose from the
following "limited time only" offers:
- Offer 1:
Six Ways to Make Your Life Easier in the Lab: Choose from one
of six value-packed hardware or software packages (Worldwide).
With the purchase of a new Finnigan LCQ™ Deca XP MAX, you can
qualify for...
- Offer 2: Increase your
instrument sensitivity and throughput - Trade In and Trade Up
your LCQ Ion Trap (North America Only). Upgrade your Finnigan
LCQ ion trap to the proven performance of the Finnigan LCQ
Deca XP MAX at a substantially lower... |
| More
Information |
| Trap Talk: Finnigan
LC/MS Ion Trap Product Portfolio |
|
| The Finnigan
ion trap mass spectrometer product line features a four-tier
portfolio to support a full spectrum of analytical
requirements. These instruments support applications ranging
from compound identification and routine HPLC through to the
most demanding analyses of low-level components in complex
biological matrices. With market and technology leadership
based on over 25 years of pioneering ion-trap development. The
Finnigan LTQ FT™,
Finnigan LTQ™,
Finnigan LCQ Deca XP MAX and Finnigan LCQ Advantage MAX
represent technology you can trust. |
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| Learn
more |
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| For additional
information |
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property of Thermo Electron Corporation and its
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