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| Thermo at Pittcon
2006: Booth # 3733 |
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Look Closer at
New Life Sciences Mass Spectrometry Solutions from
Thermo:
- innovative new hybrid mass spectrometers - the
LTQ Orbitrap™ and Finnigan™ LTQ FT™
- new end-to-end
solutions with triple quadrupole mass spectrometers equipped
with LCquan™ 2.5 (interfaces with Watson LIMS™) and
QuickQuan
- new linear ion trap mass spectrometer namely,
the Finnigan LXQ™ expands on the distinguished Finnigan LTQ™
product line
- new refractive index and fluorescense
detectors for HPLC |
| Look Closer
Now! |
| Tip of the Month:
Detecting a Blocked Ion Transfer Capillary |
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| The bore of the ion
transfer capillary can become blocked by buffer salts or high
concentrations of sample. If the pressure in the ion transfer
capillary-skimmer region (as measured by the Convectron gauge)
drops considerably below 1 Torr, one can suspect a blocked ion
transfer capillary. This indicates that the ion transfer
capillary needs to be removed and cleaned. |
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| Proteomics:
Complementary Analysis of Human CSF
Proteins |
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Electrospray and
matrix-assisted laser desorption ionization (MALDI) are both
commonly used to generate biomolecular ions for mass
spectrometry analysis. Findings from previous studies have
shown that both ionization techniques can be complementary
and, when combined, can greatly improve proteome coverage and
overall protein identification in complex protein mixtures.
This study utilizes Thermo’s Finnigan LTQ (linear ion trap)
mass spectrometer with the combined workflow of nano LC-MS/MS
(electrospray mode) and LC-MALDI/MS/MS with the vMALDI source
to evaluate... |
| Download Full
Article [PDF 243 kB] |
| Quantum Waves:
Detecting Nitrofuran Metabolites in Honey |
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| Nitrofurans are
broad-spectrum antibiotics used to treat bees and other
animals with bacterial infections. As a result of dosing bees
with these antibiotics their metabolites are sometimes found
in honey. Female rats given nitrofurans in both low and high
doses have exhibited increased incidences of ovarian granulose
cell tumors. In the same study, newborn mice showed an
increased incidence of pulmonary papillary adenomas. As a
result, nitrofurans have been banned from use in
food-producing animals in several countries. Studies have
shown that animals rapidly metabolize nitrofurans within a few
hours. So detection has focused on the metabolites rather than
the native drug. |
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| Download Full
Article [PDF 223 kB] |
| Small
Molecule Seminars - Asia/Europe/Canada |
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Register now to
attend informative sessions on compound identification and
bioanalysis. The new Finnigan LXQ and LTQ Orbitrap mass
spectrometers deliver more confident compound identification
faster, utilizing Data Dependent™ techniques and accurate mass
capabilities, respectively. The sessions will also cover two
software packages that enable small molecule quantitation:
QuickQuan for automated high-throughput discovery quantitation
and LCquan 2.5 that provides 21 CFR Part 11 compliance with
seamless integration to Watson LIMS. |
| Learn more and
Register now |
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| 2006-2007 Thermo Wall
Calendar |
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| Request your free
2006-2007 Thermo wall calendar. |
| Order
Now |
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| 2006-2007 Columns and
Consumables Catalog |
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| Request your copy of the
2006-2007 consumables catalog. |
| Order
Now |
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| Software: BioWorks
3.2 Engineering Fix 1 |
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| BioWorks 3.2 EF1
(Engineering Fix 1) is available as a free download for users
of BioWorks 3.2. This enhances the performance of BioWorks and
it is recommended that all users of this program download and
install this update. |
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| Download BioWorls
3.2 EF 1 Now |
| Metabolomics
Scientific Meeting |
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Metabolomics
society presents Metabolomics 2006, the second scientific
meeting of the Metabolomics society in Boston, USA. Topics
include metabolomics technologies, metabolomics in healthcare,
lipid maps and lipidomics, plant metabolomics, databases,
structures and informatics, environmental metabolomics,
etc. |
| Learn
More |
| Trap Talk: Advanced
Data Dependent Analysis |
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| Data Dependent acquisition
using Finnigan Ion Trap mass spectrometers allows automated
real-time decisions for subsequent MSn analysis. This enables
mass spectrometers to acquire data selectively without any
user intervention, which is important for automated structural
identification, sequence determination and unknown compound
confirmation. This Data Dependent technology is particularly
well-suited to ion trap mass spectrometers due to... |
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| Download Full
Article [PDF 63
kB] |
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