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| Thermo at ASMS 2006:
Booth 77 |
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Thermo has
several events planned for ASMS 2006.
- User
meeting: This application-focused forum will take place on
Sunday, May 28 beginning at 7:30 A.M. at the Westin Hotel,
Grand Ballrooms 1 and 2. The meeting will feature two workshop
tracks: proteomics and small molecules.
- Annual
customer appreciation event: The customer appreciation
event will begin right after the customer forum and will
feature a behind-the-scenes tour of the Safeco field, home of
the Seattle Mariners professional baseball team.
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Hospitality suite: The hospitality suite will be open
throughout the conference at the Westin Hotel Grand Ballroom 1
from 6:30pm until 9:30pm. |
| Learn more and
register now |
| Tip of the month:
XReport 1.0 |
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| XReport software is the
new reporting package tool for the Xcalibur Data System.
XReport is designed with ease of use in mind--providing a
flexible visual interface environment for intuitive
drag-and-drop template and report generation. Creation of anny
report template, simple or complex, is equally fast and easy
with XReport. |
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| Learn
more |
| Thermo obtains
exclusive license for the use of ETD
technology |
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Thermo has
obtained an exclusive license for Electron Transfer
Dissociation (ETD) technology from the Universoty of Virginia.
ETD is an innovative new ion fragmentation technology that
provides sequence information not available from conventional
methods currently in use on ion trap mass spectrometers. "ETD
will help shed new light on many important, unanswered
questions in contemporary biology,” said Dr. Don Hunt,
principal investigator at the University of Virginia. “ETD
represents a landmark advance in the field of proteomics. This
new methodology is a powerful and reliable analytical solution
for protein characterization." |
| Learn
more |
| Biomarkers
Webinar |
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Title: Bottom-up,
label-free, high-throughput differential analysis of human
plasma using an integrated fractionation/nano-ESI device
coupled with LC-FTMS detection
Presenter: Jennifer
Sutton, Ph.D., Thermo Electron
Abstract:
Identification of protein/peptide biomarkers in plasma is a
daunting analytical task due to the extremely high
concentration, wide dynamic range, and sample complexity of
this biological fluid. Intrinsic to traditional bottom-up
strategies is the further increase in complexity of the
original protein sample when it is digested into peptides.
Multidimensional separations have been employed in an effort
to ameliorate this problem. In this presentation, an
alternative strategy for high-throughput differential analysis
of human plasma is demonstrated, based on a fully automated,
robust post-column split experiment in combination with
gas-phase fractionation. |
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| View webinar
recording |
| Quantum Waves:
Selectivity improvement for drug urinalysis using FAIMS and
H-SRM |
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When developing
LC-MS methods, reference standards are used to establish
initial conditions. Applying these initial conditions to
real-world biological samples presents significant challenges
including reduced signal-to-noise ratio (S/N). Biological
matrices add interferences and contribute to reduced method
selectivity. Bioanalytical scientists have many tools to solve
selectivity problems that arise during method
development. |
| Download full
article [PDF 142 kB] |
| Proteomics:
Site-specific identification of residues in peptides using
MALDI |
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| Oxidative
post-translational modifications are increasingly considered
important, particularly for research associated with aging,
cardiovascular disease and environmentally associated
inflammation. These modifications involve reactive oxygen and
nitrogen species with reactions such as nitration or
nitrosylation of specific amino acids. Using proteomics tools
such as mass spectrometry, it may be possible to simplify
detection and screening of multiple modifications.
Identification and localization of 3-nitrotyrosine residues in
peptides... |
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| Download full
article [PDF 400
kB] |
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| Metabolomics
Scientific Meeting |
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| Metabolomics society
presents Metabolomics 2006, the second scientific meeting of
the Metabolomics society in Boston, USA. Topics include
metabolomics technologies, metabolomics in healthcare, lipid
maps and lipidomics, plant metabolomics, databases, structures
and informatics, environmental metabolomics, etc. |
| Learn
more |
| Proteomics Resource
CD |
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The resource library CD
includes:
- ETD and PQD dissociation applications
-
SIEVE differential expression protocols
- Top-down protein
analysis with the Finnigan™ LTQ FT™
- PTM analysis using
the Finnigan vMALDI™ ion source
- Protein quantification
using the LTQ Orbitrap™
- 2005 proteomics seminar
presentations
- Technical posters from HUPO 2005
- ABRF
2006 posters and presentations and more... |
| Request CD
now |
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| CoSMoS
2006 |
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| The Conference on Small
Molecule Science addresses the latest in small molecule
science topics in a unique, intimate setting. This innovative
research-style meeting promotes high-level discussions
focusing on the exchange of practical experience and ideas,
academic research and novel techniques. |
| Learn
more |
| Environmental &
food safety applications CD |
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The new environmental and
food safety applications CD contains methods of analysis for
several chemicals including the following:
- Pesticides in
red pepper
- Micropollutant benzofluoranthenes
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Pesticides in water
- Food residues in lemon, onion and
salad extracts and more...
Obtain your copy today by
contacting your nearest sales representative. |
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| Thermo at IMSC 2006 -
Prague Congress Centre, Prague, Czech
Republic |
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Thermo is pleased
to present its full range of state-of-the-art instrument
systems, advanced software, and innovative column technology
at IMSC 2006. Learn more from our experts about the latest
cutting edge developments in instrumentation - ion trap,
quadrupole, hybrid, magnetic sector mass spectrometers, and
hyphenated multi-instrument combinations of
products.
Watch this space for further
information. |
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| Small Molecule
Seminars - Europe/Canada |
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| Register now to attend
informative sessions on compound identification and
bioanalysis. The new Finnigan LXQ™ and LTQ Orbitrap mass
spectrometers deliver more confident compound identification
faster, utilizing Data Dependent™ techniques and accurate mass
capabilities, respectively. The sessions will also cover two
software packages that enable small molecule quantitation:
QuickQuan for automated high-throughput discovery quantitation
and LCQUAN 2.5 that provides 21 CFR Part 11 compliance with
seamless integration to Watson™ LIMS. |
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| Learn more and
register now |
| Trap
Talk: Nature and extent of metabolism |
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Traditionally,
metabolic stability and metabolite profiling experiments are
carried out as two separate assays. Metabolic stability is
determined from an LC-MS analysis in SIM or SRM mode whereas
metabolite identification and characterization requires an
LC-MSn experiment. This paper discusses a strategy that
involves the simultaneous determination of the nature and
extent of metabolism by performing metabolite identification
and metabolic stability measurements in a single analytical
run. |
| Download Full
Article [PDF 112
kB] |
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