| Tip
of the Month: Parent Mass List |
|
 |
Use of Parent
Mass List in Data Dependent Neutral Loss MS³ experiments
allows for targeted analysis of expected compounds in neutral
loss experiments. It is also useful when parent ions are
known, but of low intensity. |
| See
How |
| Metabolite Profiling
and Characterization: A High-throughput
Approach |
|
| Within the drug discovery
environment, high sample throughput that provides
comprehensive drug metabolite identification and profiling is
a key requirement. Traditionally, triple quadrupole
instruments using selected reaction monitoring (SRM or MRM)
have been employed; however, SRM and MRM studies do not
necessarily detect all of the drug metabolites being
investigated. Additional detection methods including precursor
ion and neutral loss scanning are often... |
 |
| Download Full
Article [PDF 1210 kB] |
| Analysis of
High-Boiling Point Components in Petroleum using a Single
Quad |
|
 |
The analysis of
petroleum feedstock and finished products is traditionally
achieved using gas chromatography (GC) coupled to a number of
detectors, the most sensitive and selective being the mass
spectrometer. One of the major obstacles to routine analysis
for the heavier-cut petrochemical products using GC/MS methods
has been the ability to volatilize the high-boiling
components. LC/MS methods do not suffer the limitation of
volatility or... |
| Download Full
Article [PDF 832 kB] |
| Proteomics Pioneers
Vol. 5 By GenomeWeb News |
|
This issue of Proteomics
Pioneers features 5 interviews with proteomics researchers
whose research depends on mass spectrometry. The issue
features:
- Michael Gross on Diabetes and Other Work at
Wash U’s MS Research Resource
- Fourier Transform Mass
Spectrometers Are Good, But They Can Be Improved
- USDA’s
Bret Cooper on Using Bean and Soybean Rust
- CSHL’s Mike
Myers on Using MS to Study Post-Translational
Modifications
- RTI’s Jim Stephenson on IPG Strips and the
Reliability of MS Data |
 |
| Download Full
Issue [PDF 591 kB] |
| Visit
Thermo at the 23rd Montreux LCMS Symposium, Montreux,
Switzerland |
|
 |
Thermo is pleased
to invite you to the 23rd Montreux LC/MS Symposium. Thermo's
User Meeting and Workshop will focus on the latest
developments in technology and applications in the Small
Molecule arena, topics will cover MetWorks, Metabolomics, Food
Safety, Environmental and Bioanalysis. |
| Learn More and
Register Now |
| We Want To Hear From
You About Your Software |
|
| We want to hear from you!
We are continually trying to meet and exceed the demands of
our customers. Please give us feedback on the functionality of
your software, or submit a specific request for an added
feature! |
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| Send Us Your
Feedback Now |
| Learning
Opportunity |
|
 |
Learn with
various courses offered by Thermo. Chromatography courses
include PolarisQ, TRACE™ DSQ, ToxLab™, Basic LC/MS, HPLC and
GC operations, Xcalibur™ software module, ChromQuest™ Software
module, Surveyor MSQ™ Plus, EI/CI interpretation and more.
Mass Spectrometry courses include LCQ™, LXQ™, LTQ™, LTQ FT™,
LTQ Orbitrap™, TSQ™ Quantum, BioWorks™ and more. |
| Learn More and
Register Now |
| Trap Talk: High
Resolution Isolation |
|
| MSⁿ analysis of ions in an
ion trap mass spectrometer is a differentiating technique for
the structural identification of a wide variety of compounds.
The simplest approach involves, isolating ions with a specific
m/z value of interest, energetically exciting these ions,
generating fragment ions through collisions with a buffer gas,
and performing mass analysis of the fragments produced. The
isolation step is critical to the process since... |
 |
| Download Full
Article [PDF 162
kB] |
|
