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| Tip
of the Month: Rejection of Unassigned Charged
States |
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Unassigned charge
states can be skipped in Data Dependent experiments. The
benefit of skipping unassigned charge states is that more of
the linear trap duty cycle is devoted to scanning of ions of
interest. |
| See
How |
| Webinar: EQuan™
System for Environmental and Drinking Water
Analysis |
|
EQuan is a turnkey system
incorporating the TSQ Quantum™ for the analysis of pesticides,
herbicides, antimicrobials, antibiotics and other
pharmaceuticals in environmental and drinking water samples.
Join this webinar to learn about EQuan’s unique on-line sample
enrichment technique that significantly reduces analysis time
– from days to minutes – while still giving you the
sensitivity and specificity required. Presented by Jonathan
Beck, Ph.D., this webinar includes an explanation of the EQuan
system, plus real-life data from EQuan customers, including
the Laboratoire Department de L’eau in Toulouse,
France.
|
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| View Webinar Now
[25 Mins.] |
| Proteomics:
High-Throughput Quantitative Proteomics on a Triple
Quad |
|
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A common endpoint
for a biomarker discovery experiment is a list of putative
marker proteins. A reasonable next step is to then perform
targeted quantitative measurements of these proteins in an
expanded patient population to assess their validity as
markers. Analytical accuracy and precision are required for
unambiguous quantitative analysis of targeted proteins from
very complex mixtures. Wide dynamic range and high sensitivity
are critical for detecting low abundance proteins. One
approach for this application is the use of tandem mass
spectrometry to... |
| Download Full
Article [PDF 345 kB] |
| Proteomics Resource
Library 2.2 |
|
The Proteomics Resource
Library 2.2 is now available. This release of the library
includes proteomics technical content from:
- ASMS
2005/2006
- ABRF 2005/2006
- HUPO 2005/2006
- IMSC
2006
- 2005/2006 Proteomics Seminar Presentations
-
2005/2006 Proteomics Application Notes |
 |
| Request your
Resource Library Now |
| Software
Update |
|
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Starting with the
current issue of Critical Mass, we will be featuring a section
titled "Software Update" providing you information about the
latest software releases from Life Sciences Mass Spectrometry
at Thermo Scientific. Please contact your local sales
representative regarding questions on how to upgrade your
software. We hope this will help you keep up-to-date with the
latest software releases.
Note: This list is subject
to change without notice as our software is continuously being
updated and improved. |
| See the latest
Software Update Information
Now |
| Drug Discovery:
Mechanisms of Ion Formation for Famotidine and
Azithromycin |
|
| Famotidine is in a class
of medications called histamine H2-receptor antagonists and is
being used to treat ulcers and gastroesophageal reflux
disease. Azithromycin (Zythromax) is a semi-synthetic
macrolide antibiotic which is effective against a wide variety
of bacteria organisms. Azithromycin has a long half-life
allowing for once a day dosing and for shorter treatment
courses for most infections. Mass spectrometry has... |
 |
| Download Full
Article [PDF 306 kB] |
| LCQ
Trade-In Promotion |
|
 |
Get the most out
of your LCQ asset by trading-in and trading-up to the latest
linear ion trap technology. Don't miss out on this limited
time promotional trade-in offer. Trade in your LCQ regardless
of condition or LCQ model, and receive a significant trade-in
discount on the exciting LXQ or LTQ XL Linear Ion Trap.* |
| Learn
More |
| Trap Talk:
Optimization of Parameters for Performing ETD on 2D
Traps |
|
| Electron transfer
dissociation (ETD) on a linear ion trap has been demonstrated
to be an extremely powerful dissociation technique for
characterization of larger multiply charged peptide and
proteins. In implementing the ETD technique, there are many
parameters, which must be considered in order to optimize its
performance and produce informative, interpretable data. These
parameters include those associated with forming and
delivering the reagent ions, storing the reagent and analyte
ions simultaneously, and the ion-ion reaction conditions. |
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| Download Full
Article [PDF 596
kB] |
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