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| Tip
of the Month: Calibration File Backup and
Restore |
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Calibration file
backup and restore allows saving and restoring calibration
files. It is useful for different calibration samples,
especially for high-mass calibration sample. |
| See How to Access
this Feature |
| Software
Update |
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Here are the software
updates for December. There have been several since the last
revision. Please contact your local sales representative
regarding questions on how to upgrade your
software.
Note: This list is subject to change
without notice as our software is continuously being updated
and improved. |
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| View the Latest
Software Updates |
| Environmental
Application: Anti-Infectives in Raw and Treated
Sewage |
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“Anti-infectives”
is a general term that refers to several classes of
biologically active compounds used to treat or prevent
infections. Therapeutic agents such as antimicrobials
(synthetic) and antibiotics (natural or semi-natural) are
examples of anti-infectives. The widespread utilization of
anti-infectives in urban centers as well as their resistance
to biodegradation or elimination in wastewater treatment
plants (WWTPs) has led to their appearance in effluents and
surface waters. In the last few years there has been a growing
concern about the environmental fate and the possible effects
of these agents on the aquatic environment. |
| Download Full
Article [PDF 269 kB] |
| Drug Discovery: CID
of Methimazole and Acetylsalicylic Acid |
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| Acetylsalicylic acid
(Aspirin) belongs to a class of medications known as
non-steroidal anti-inflammatory drugs (NSAIDs) and has been
among the most popular medications for treating mild to
moderate pain. It also reduces inflammation, clotting of
blood, fever, redness, swelling and discomfort caused by
medical disorders such as headaches, infections and arthritis.
Methimazole is used to treat hyperthyroidism, a condition that
occurs when the thyroid gland produces too much thyroid
hormone. Mass spectrometry has played a significant role in
the characterization and analysis of small molecules such as
Methimazole and Aspirin. |
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| Download Full
Article [PDF 268 kB] |
| Thermo Fisher
Scientific Acquires Cohesive Technologies |
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Thermo Fisher
Scientific recently acquired Massachusetts-based Cohesive
Technologies Inc., a manufacturer of advanced sample
extraction and liquid chromatography products. The Cohesive
product line enhances the company's Thermo Scientific-branded
portfolio by adding in-line sample preparation capabilities
that couple with mass spectrometry technology to create
end-to-end workflow solutions for drug and other organic
molecule analyses. These new capabilities will significantly
improve sample throughput and increase detection limits during
LC/MS/MS analysis for customers in the pharmaceutical,
clinical, environmental and food science industries. |
| Read Full Press
Release |
| Resource
Centre |
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Multiple information
packed CDs are a mere click away. Make use of this opportunity
to order one or more of the following resources:
-
Proteomics Resource Library 2.2 CD
- 2006 LC/MS
Presentations CD
- LC/MS Abstracts Database Rev 1.3 CD
-
Laminated 2007 Wall Calendar
- Columns and Consumables
catalog |
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| Place your Order
Now |
| Proteomics
Application: Relative Quantitation on an LTQ
Orbitrap |
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Accurate
quantitation of differentially expressed proteins is a
continuing challenge in proteomics research. Many analytical
methods have been developed, including several isotope
labeling techniques. LC-MS/MS with linear ion trap technology
is a proven method for sensitive and robust protein
identification in "bottom-up" experiments. Quantitation of low
mass reporter ions created during MS/MS analysis of iTRAQ
labeled peptides can be performed... |
| Download Full
Article [PDF 255 kB] |
| Trap Talk: Increased
Post-Excitation Ion Cyclotron Radius |
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| In Fourier transform ion
cyclotron resonance (FTICR) mass spectrometry, high
post-excitation cyclotron radii are beneficial in terms of
both detection sensitivity and mass accuracy. However, in
conventional ICR cells, the maximum attainable post-excitation
radius usually is limited by axial components of the
excitation field causing the loss of ions due to axial
ejection. Various ICR cell designs have been introduced over
the... |
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| Download Full
Article [PDF 1,832
kB] |
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