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| Tip
of the Month: Positive and Negative Polarity Data Dependent
Settings |
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Separate positive
and negative polarity data dependent settings allows separate
parent, reject and neutral loss mass lists for positive and
negative events respectively. In addition, it allows for
separate MSn settings for positive and negative polarity
events such as thresholds and activation energies. |
| See
How |
| All Molecule World
Tour: Feb 2 - May 10 2007 |
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Register to attend a free
seminar on the latest LC/MS methods for:
- protein
analysis
- compound identification
- bioanalysis
-
environmental
- food safety
The tour will feature
various industry leaders and application experts. |
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| Learn More and
Register Now |
| Proteomics: Targeted
Quantitative Protein Analysis on A Triple
Quad |
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A common endpoint
for a biomarker discovery experiment is a list of putative
marker proteins. A reasonable next step is to then perform
targeted quantitative measurements of these proteins in an
expanded patient population to assess their validity as
markers. Analytical accuracy and precision are required for
unambiguous quantitative analysis of targeted proteins from
very complex mixtures. Wide dynamic range and high sensitivity
are critical for... |
| Download Full
Article [PDF 819 kB] |
| Software
Update |
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Here are the software
updates for January 2007. Please contact your local sales
representative regarding questions on how to upgrade your
software.
Note: This list is subject to change
without notice as our software is continuously being updated
and improved. |
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| View Updates
Now |
| LC/MS
with TurboFlow® Technology |
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Thermo Fisher
Scientific recently acquired Cohesive Technologies, the
manufacturer of advanced online sample extraction systems that
employ patented TurboFlow technology, to provide customers
with a complete end-to-end LC-MS/MS solution. The Aria TLX
systems are first choice in bioanalytical labs because they
nearly eliminate the time consuming sample prep process while
significantly increasing productivity, sensitivity, and
selectivity. Aria Systems with TurboFlow methods minimize ion
suppression for sample extracts, which is a significant
advantage compared to SPE and PPT. As a result, it is the
preferred method for sample preparation of biological
fluids. |
| Read a few
applications to learn
more |
| LC/MS Abstracts
Database CD |
|
The LC/MS Abstracts
Database CD, now available, includes:
- Over two thousand
LC/MS abstracts
- 50+ PTM analysis abstracts
- 75+
biomarker-related abstracts
- 100+ MALDI application
abstracts
- 200+ proteomics application abstracts
-
Top-down, bottom-up, and high-throughput protein ID
- LTQ
Orbitrap, LTQ FT, TSQ Quantum, and MSQ applications
Don't
miss out on these many new applications. |
 |
| Request your free
copy now |
| Food
Safety: Automated Sample Cleanup using Red Wine as a
Matrix |
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Achieving low
limits of detection (LODs) of pesticides, antibiotics and
veterinary residues in food residues and drinking water is of
paramount importance in order to monitor the regulatory levels
as stated by the US, Japanese and EU directives. These
substances pose a significant health threat and therefore,
need to be accurately detected at the lowest levels, typically
at part per trillion (ppt). |
| Download Full
Article [PDF 545 kB] |
| Trap Talk: Single Ion
Monitoring with High Mass Accuracy |
|
| Recent work in proteomics
research demonstrates the need to identify peptides and
proteins in complex mixtures from biological sources at
extremely low levels with the highest confidence. This is
facilitated by the use of a mass spectrometer with high
dynamic range and high mass accuracy. Moreover, for MS/MS
experiments, fast scan repetition rates at highest sensitivity
are needed. |
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| Download Full
Article [PDF 325
kB] |
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