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  Custom HeavyPeptides™


Kits for Relative and Absolute Quantitation in Proteomics

HeavyPeptide BASIC and AQUA are the first kits that offer a complete solution for both absolute and relative quantitation of proteins by Mass Spectrometry (MS).  ™

Protein Quantitation by Mass Spectrometry

One of the key challenges in Proteomics is the quantitation of proteins at very low concentrations in complex protein mixtures. Thermo Fisher Scientific one of the world's leading manufacturers of mass spectrometers has a large base of customers confronted daily with these challenges and was also the first company to install a pilot research center dedicated to Biomarker Discovery (BRIMS2, in Boston, MA)

Carefully listening to these end-users led us to the development of a fast, economical, and easy-to-use solution: Custom HeavyPeptide Basic and AQUA kits.
   Product Detail


HeavyPeptides are isotopically-labelled, non-radioactive custom peptides for Mass Spectrometry (MS) and Nuclear Magnetic Resonance (NMR) Spectroscopy applications. They can be used as sequence-identical internal weight standards for quantitation of proteins and protein mixtures.

Researchers can choose from a variety of custom-made HeavyPeptide kits to preform relative or absolute quantitation, including the AQUA technique, developed by Harvard Medical School. Combined with Thermo Fisher Scientific's high performance range of MS instruments, such as the Finnigan™ LTQ FT™, customers have access to the most powerful tools in Proteomics.

Advantages

  • relative or absolute quantitation
  • higher accuracy, sensitivity and specificity
  • easy to order custom-made HeavyPeptides
  • quantitation of low abundance proteins
  • economically viable for high throughput screening

Applications

  • biomarker discovery and validation
  • pharmacokinetics
  • metabolomics
  • clinical biochemistry (drug and metabolite monitoring)
  • anti-doping testing
  • protein expression rating
  • validation of siRNA experiments
  • cell signaling profiling

More technical information

 
 Custom HeavyPeptides™
 Product# Price  kit type  isotopic label  
         
 300100      -    HeavyPeptide AQUA demo kit 1 HeavyPeptide, 1 LightPeptide, tryptic protein digest   SELECT  
 200200      -    HeavyPeptide BASIC yes   SELECT  
 200201      -    HeavyPeptide BASIC 1 Phos yes   SELECT  
 200202      -    HeavyPeptide BASIC 2 Phos yes   SELECT  
 200205      -    LightPeptide BASIC no   SELECT  
 200206      -    LightPeptide BASIC 1 Phos no   SELECT  
 200207      -    LightPeptide BASIC 2 Phos no   SELECT  
 300210      -    HeavyPeptide AQUA yes   SELECT  
 300211      -    HeavyPeptide Aqua 1 Phos yes   SELECT  
 300212      -    HeavyPeptide AQUA 2 Phos yes   SELECT  
 300215      -    LightPeptide AQUA  no   SELECT  
 300216      -    LightPeptide AQUA 1 Phos no   SELECT  
 300217      -    LightPeptide AQUA 2 Phos no   SELECT  
 300220      -    HeavyPeptide AQUA XL  yes   SELECT  
 300221      -    HeavyPeptide AQUA XL 1 Phos yes   SELECT  
 300222      -    HeavyPeptide AQUA XL 2 Phos yes   SELECT  
 300225      -    LightPeptide AQUA XL no   SELECT  
 300226      -    LightPeptide AQUA XL 1 Phos no   SELECT  
 300227      -    LightPeptide AQUA XL 2 Phos no   SELECT  
 
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